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The pump system should not be implanted until the patient’s response to bolus LIORESAL INTRATHECAL injection is adequately evaluatedEvaluationconsisting of a screening proceduresee Dosage and Administrationrequires that LIORESAL INTRATHECAL be administered into the intrathecal space via a catheter or lumbar punctureBecause of the risks associated with the screening procedure and the adjustment of dosage following pump implantationthese phases must be conducted in a medically supervised and adequately equipped environment following the instructions outlined in the Dosage and Administration section.
Symptoms of LIORESAL INTRATHECAL OverdoseDrowsinesslightheadednessdizzinesssomnolencerespiratory depressionhypothermiaseizuresrostral progression of hypotonia and loss of consciousness progressing to coma of up to 72 hrdurationIn most cases reportedcoma was reversible without sequelae after drug was discontinuedSymptoms of LIORESAL INTRATHECAL overdose were reported in a sensitive adult patient after receiving a 25 mcg intrathecal bolus.
The following laboratory tests have been found to be abnormal in a few patients receiving Lioresalincreased SGOTelevated alkaline phosphataseand elevation of blood sugar.
Baclofen is used to treat muscle spasms caused by certain conditionssuch as multiple sclerosisspinal cord injury/diseaseIt works by helping to relax the muscles.
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